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| Methotrexate (Rheumatrex, Trexall) |
How do I use Methotrexate? Take Methotrexate exactly as prescribed, and promptly report to your doctor any new symptoms that may develop. The dosage to treat cancer is higher than for psoriasis or rheumatoid arthritis. After high-dose Methotrexate treatment, a medicine called leucovorin may be given to limit the toxic effects. Remember that in the treatment of psoriasis and rheumatoid arthritis, Methotrexate is taken once a week, not once a day. Accidentally taking the recommended weekly dosage on a daily basis can lead to fatal overdosage. Be sure to read the patient instructions that come with the package. What are the potential side effects from Methotrezate? More frequent side effects from Methotreaxte may include: Abdominal pain and upset, chills and fever, decreased resistance to infection, dizziness, fatigue, general feeling of illness, mouth ulcers, nausea. Less common side effects from Methotrexate may include: Abortion, acne, anemia, birth defects, black or tarry stool, boils, bruises, changes in skin coloration, convulsions, diarrhea, drowsiness, eye or vision problems, fatigue, hair loss, headaches, hives, sore throat, stomach and intestinal ulcers and bleeding, stomach pain, vaginal discharge, vomiting blood. What should I discuss with my doctor before taking Methotrexate? Consult your doctor if you have any of the following conditions: If you are sensitive to it or it has given you an allergic reaction, If you suffer from psoriasis or rheumatoid arthritis and also have one of the following conditions: Abnormal blood cell count, Alcoholic liver disease or other chronic liver disease, Alcoholism. If you are pregnant or plan to become pregnant, check with your doctor. If you are planing to combine alcoholic beverages while taking this drug, consult your doctor. Before receiving an immunization or vaccination, be sure to inform health care workers that you are taking this drug. What is the recommended dose for Methotrexate? Treatment with methotrexate is highly individualized. Your doctor will carefully tailor your dosage of methotrexate in order to avoid serious side effects and possible under or overdosing. What should I do in case of an overdose with Methotrexate? Taken in excess, methotrexate can cause serious and even fatal damage to the liver, kidneys, bone marrow, lungs, or other parts of the body. Symptoms of overdosage may include lung or breathing problems, mouth ulcers, or diarrhea. Initially, however, serious damage caused by methotrexate may be apparent only in the results of blood tests, seek medical attention as soon as possible, if you suspect overdose. |
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