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What is phenobarbital? Phenobarbital is in a group of drugs called barbiturates (bar-BIT-chur-ates). Phenobarbital slows the activity of your brain and nervous system. Phenobarbital is used to treat or prevent seizures. It is also used short-term to treat insomnia, or as a sedative before surgery. Phenobarbital may also be used for other purposes not listed in this medication guide. What is the most important information I should know about phenobarbital? Phenobarbital may cause a severe allergic reaction. Stop taking phenobarbital and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Do not stop using phenobarbital without first talking to your doctor, even if you feel better. You may have increased seizures if you stop using phenobarbital suddenly. You will need to use less and less before you stop the medication completely. Take phenobarbital only when you are getting ready for several hours of sleep. You may fall asleep very quickly after taking the medicine. Some people using this medicine have engaged in activity such as driving, eating, or making phone calls and later having no memory of the activity. If this happens to you, stop taking phenobarbital and talk with your doctor about another treatment for your sleep disorder. What should I discuss with my healthcare provider before taking phenobarbital? Some people using this medicine have engaged in activity such as driving, eating, or making phone calls and later having no memory of the activity. If this happens to you, stop taking phenobarbital and talk with your doctor about another treatment for your sleep disorder. Do not take this medication if you are allergic to phenobarbital, or if you have porphyria. Before taking phenobarbital, tell your doctor if you are allergic to any drugs, or if you have:
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